Abacavir is an NRTI that was approved in 1998. lt is generally well tolerated with few side effects, at the start of taking abacavir some people may feel nauseous, general malaise and fatigue which will usually clear up within a few weeks. Before taking abacavir it is advised to take the HLA-B*5701 genetic blood test to check for any hypersensitivity. Take once or twice a day with or without food. While taking abacavir regular liver function testing is recommended. It is one of the medications contained in EPZICOM and TRIUMEQ. Do not take with ritonavir. Inform your doctor if you have any history of alcoholism.